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Formulation and Characterization of Gum Arabic Stabilized Red Rice Extract Nanoemulsion

Interest in the utilization of plant-based bioactive compounds in foods has increased due to their biochemical activities and as alternatives in the reduction of high concentrations of chemical utilization. However, some of these additives are hydrophobic, thus being harder to disperse into the hydr...

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Autores principales: Bains, Aarti, Najda, Agnieszka, Chawla, Prince, Klepacka, Joanna, Dhull, Sanju Bala, Sadh, Pardeep Kumar, Khan, Mohammed Azhar, Kaushik, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146556/
https://www.ncbi.nlm.nih.gov/pubmed/35631821
http://dx.doi.org/10.3390/polym14101938
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author Bains, Aarti
Najda, Agnieszka
Chawla, Prince
Klepacka, Joanna
Dhull, Sanju Bala
Sadh, Pardeep Kumar
Khan, Mohammed Azhar
Kaushik, Ravinder
author_facet Bains, Aarti
Najda, Agnieszka
Chawla, Prince
Klepacka, Joanna
Dhull, Sanju Bala
Sadh, Pardeep Kumar
Khan, Mohammed Azhar
Kaushik, Ravinder
author_sort Bains, Aarti
collection PubMed
description Interest in the utilization of plant-based bioactive compounds in foods has increased due to their biochemical activities and as alternatives in the reduction of high concentrations of chemical utilization. However, some of these additives are hydrophobic, thus being harder to disperse into the hydrophilic food matrix. Therefore, an oil-in-water nanoemulsion (RRE1-RRE10) was formulated with different concentrations of red rice extract (1–10% w/v). Nanoemulsion showed droplet sizes within the range of 157.33–229.71 nm and the best formulation (RRE5) was selected based on the creaming index which was stable to flocculation over a range of temperatures (30–90 °C), pH (2–9), and salt concentration (100–600 mM). It showed significantly improved antioxidant and anti-inflammatory activity as compared to its other counterparts. Potential antimicrobial activity against Staphylococcus aureus was attributed to RRE5 nanoemulsion as compared to Escherichia coli. Therefore, due to the potential bioactivity of RRE5 nanoemulsion, it can be scaled up at the industrial level.
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spelling pubmed-91465562022-05-29 Formulation and Characterization of Gum Arabic Stabilized Red Rice Extract Nanoemulsion Bains, Aarti Najda, Agnieszka Chawla, Prince Klepacka, Joanna Dhull, Sanju Bala Sadh, Pardeep Kumar Khan, Mohammed Azhar Kaushik, Ravinder Polymers (Basel) Article Interest in the utilization of plant-based bioactive compounds in foods has increased due to their biochemical activities and as alternatives in the reduction of high concentrations of chemical utilization. However, some of these additives are hydrophobic, thus being harder to disperse into the hydrophilic food matrix. Therefore, an oil-in-water nanoemulsion (RRE1-RRE10) was formulated with different concentrations of red rice extract (1–10% w/v). Nanoemulsion showed droplet sizes within the range of 157.33–229.71 nm and the best formulation (RRE5) was selected based on the creaming index which was stable to flocculation over a range of temperatures (30–90 °C), pH (2–9), and salt concentration (100–600 mM). It showed significantly improved antioxidant and anti-inflammatory activity as compared to its other counterparts. Potential antimicrobial activity against Staphylococcus aureus was attributed to RRE5 nanoemulsion as compared to Escherichia coli. Therefore, due to the potential bioactivity of RRE5 nanoemulsion, it can be scaled up at the industrial level. MDPI 2022-05-10 /pmc/articles/PMC9146556/ /pubmed/35631821 http://dx.doi.org/10.3390/polym14101938 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bains, Aarti
Najda, Agnieszka
Chawla, Prince
Klepacka, Joanna
Dhull, Sanju Bala
Sadh, Pardeep Kumar
Khan, Mohammed Azhar
Kaushik, Ravinder
Formulation and Characterization of Gum Arabic Stabilized Red Rice Extract Nanoemulsion
title Formulation and Characterization of Gum Arabic Stabilized Red Rice Extract Nanoemulsion
title_full Formulation and Characterization of Gum Arabic Stabilized Red Rice Extract Nanoemulsion
title_fullStr Formulation and Characterization of Gum Arabic Stabilized Red Rice Extract Nanoemulsion
title_full_unstemmed Formulation and Characterization of Gum Arabic Stabilized Red Rice Extract Nanoemulsion
title_short Formulation and Characterization of Gum Arabic Stabilized Red Rice Extract Nanoemulsion
title_sort formulation and characterization of gum arabic stabilized red rice extract nanoemulsion
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146556/
https://www.ncbi.nlm.nih.gov/pubmed/35631821
http://dx.doi.org/10.3390/polym14101938
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