SRC Kinase-Mediated Tyrosine Phosphorylation of TUBB3 Regulates Its Stability and Mitotic Spindle Dynamics in Prostate Cancer Cells

Tubulin is an integral part of the cytoskeleton and plays a pivotal role in cellular signaling, maintenance, and division. β-tubulin is also the molecular target for taxane compounds such as docetaxel (DTX) and cabazitaxel (CTX), both first-line treatments for several solid cancers. Increased expres...

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Detalles Bibliográficos
Autores principales: Alfano, Alan, Xu, Jin, Yang, Xi, Deshmukh, Dhanraj, Qiu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146564/
https://www.ncbi.nlm.nih.gov/pubmed/35631517
http://dx.doi.org/10.3390/pharmaceutics14050932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146564/
https://www.ncbi.nlm.nih.gov/pubmed/35631517
http://dx.doi.org/10.3390/pharmaceutics14050932

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