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The Oligomeric Assemblies of Cytomegalovirus Core Nuclear Egress Proteins Are Associated with Host Kinases and Show Sensitivity to Antiviral Kinase Inhibitors

The nucleo-cytoplasmic capsid egress of herpesviruses is a unique regulated process that ensures the efficiency of viral replication and release. For human cytomegalovirus (HCMV), the core of the nuclear egress complex (NEC) consists of the pUL50–pUL53 heterodimer that is able to oligomerize and thu...

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Detalles Bibliográficos
Autores principales: Kicuntod, Jintawee, Häge, Sigrun, Hahn, Friedrich, Sticht, Heinrich, Marschall, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146606/
https://www.ncbi.nlm.nih.gov/pubmed/35632762
http://dx.doi.org/10.3390/v14051021