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Identification of Potential RBPJ-Specific Inhibitors for Blocking Notch Signaling in Breast Cancer Using a Drug Repurposing Strategy

Notch signaling is a key parameter in regulating cell fate during tissue homeostasis, and an aberrant Notch pathway can result in mammary gland carcinoma and has been associated with poor breast cancer diagnosis. Although inhibiting Notch signaling would be advantageous in the treatment of breast ca...

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Detalles Bibliográficos
Autores principales: Rui, Mengjie, Cai, Min, Zhou, Yu, Zhang, Wen, Gao, Lianglai, Mi, Ke, Ji, Wei, Wang, Dan, Feng, Chunlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146688/
https://www.ncbi.nlm.nih.gov/pubmed/35631382
http://dx.doi.org/10.3390/ph15050556