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Morphine Accumulates in the Retina Following Chronic Systemic Administration
Opioid transport into the central nervous system is crucial for the analgesic efficacy of opioid drugs. Thus, the pharmacokinetics of opioid analgesics such as morphine have been extensively studied in systemic circulation and the brain. While opioid metabolites are routinely detected in the vitreou...
Autores principales: | Bergum, Nikolas, Berezin, Casey-Tyler, Dooley, Gregory, Vigh, Jozsef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146690/ https://www.ncbi.nlm.nih.gov/pubmed/35631353 http://dx.doi.org/10.3390/ph15050527 |
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