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Exercise Normalized the Hippocampal Renin-Angiotensin System and Restored Spatial Memory Function, Neurogenesis, and Blood-Brain Barrier Permeability in the 2K1C-Hypertensive Mouse

Hypertension is associated with blood-brain barrier alteration and brain function decline. Previously, we established the 2-kidney,1-clip (2K1C) hypertensive mice model by renin-angiotensin system (RAS) stimulating. We found that 2K1C-induced hypertension would impair hippocampus-related memory func...

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Detalles Bibliográficos
Autores principales: Chang, Ying-Shuang, Lin, Chih-Lung, Lee, Chu-Wan, Lin, Han-Chen, Wu, Yi-Ting, Shih, Yao-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146761/
https://www.ncbi.nlm.nih.gov/pubmed/35628344
http://dx.doi.org/10.3390/ijms23105531