The Effect of Dynamic, In Vivo-like Oxaliplatin on HCT116 Spheroids in a Cancer-on-Chip Model Is Representative of the Response in Xenografts

The cancer xenograft model in which human cancer cells are implanted in a mouse is one of the most used preclinical models to test the efficacy of novel cancer drugs. However, the model is imperfect; animal models are ethically burdened, and the imperfect efficacy predictions contribute to high clin...

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Detalles Bibliográficos
Autores principales: Komen, Job, van Neerven, Sanne M., Bossink, Elsbeth G. B. M., de Groot, Nina E., Nijman, Lisanne E., van den Berg, Albert, Vermeulen, Louis, van der Meer, Andries D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146796/
https://www.ncbi.nlm.nih.gov/pubmed/35630206
http://dx.doi.org/10.3390/mi13050739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146796/
https://www.ncbi.nlm.nih.gov/pubmed/35630206
http://dx.doi.org/10.3390/mi13050739

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