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Are Hamsters a Suitable Model for Evaluating the Immunogenicity of RBD-Based Anti-COVID-19 Subunit Vaccines?

Currently, SARS-CoV-2 spike receptor-binding-domain (RBD)-based vaccines are considered one of the most effective weapons against COVID-19. During the first step of assessing vaccine immunogenicity, a mouse model is often used. In this paper, we tested the use of five experimental animals (mice, ham...

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Detalles Bibliográficos
Autores principales: Merkuleva, Iuliia A., Shcherbakov, Dmitry N., Borgoyakova, Mariya B., Isaeva, Anastasiya A., Nesmeyanova, Valentina S., Volkova, Natalia V., Aripov, Vazirbek S., Shanshin, Daniil V., Karpenko, Larisa I., Belenkaya, Svetlana V., Kazachinskaia, Elena I., Volosnikova, Ekaterina A., Esina, Tatiana I., Sergeev, Alexandr A., Titova, Kseniia A., Konyakhina, Yulia V., Zaykovskaya, Anna V., Pyankov, Oleg V., Kolosova, Evgeniia A., Viktorina, Olesya E., Shelemba, Arseniya A., Rudometov, Andrey P., Ilyichev, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146860/
https://www.ncbi.nlm.nih.gov/pubmed/35632800
http://dx.doi.org/10.3390/v14051060