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Quantitation of the A(2A) Adenosine Receptor Density in the Striatum of Mice and Pigs with [(18)F]FLUDA by Positron Emission Tomography

The cerebral expression of the A(2A) adenosine receptor (A(2A)AR) is altered in neurodegenerative diseases such as Parkinson’s (PD) and Huntington’s (HD) diseases, making these receptors an attractive diagnostic and therapeutic target. We aimed to further investigate the pharmacokinetic properties i...

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Detalles Bibliográficos
Autores principales: Gündel, Daniel, Toussaint, Magali, Lai, Thu Hang, Deuther-Conrad, Winnie, Cumming, Paul, Schröder, Susann, Teodoro, Rodrigo, Moldovan, Rareş-Petru, Pan-Montojo, Francisco, Sattler, Bernhard, Kopka, Klaus, Sabri, Osama, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146919/
https://www.ncbi.nlm.nih.gov/pubmed/35631343
http://dx.doi.org/10.3390/ph15050516