Biotechnological Evolution of siRNA Molecules: From Bench Tool to the Refined Drug

The depth and versatility of siRNA technologies enable their use in disease targets that are undruggable by small molecules or that seek to achieve a refined turn-off of the genes for any therapeutic area. Major extracellular barriers are enzymatic degradation of siRNAs by serum endonucleases and RN...

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Detalles Bibliográficos
Autores principales: de Brito e Cunha, Danielle, Frederico, Ana Beatriz Teixeira, Azamor, Tamiris, Melgaço, Juliana Gil, da Costa Neves, Patricia Cristina, Bom, Ana Paula Dinis Ano, Tilli, Tatiana Martins, Missailidis, Sotiris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146980/
https://www.ncbi.nlm.nih.gov/pubmed/35631401
http://dx.doi.org/10.3390/ph15050575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146980/
https://www.ncbi.nlm.nih.gov/pubmed/35631401
http://dx.doi.org/10.3390/ph15050575

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