Cargando…
Biotechnological Evolution of siRNA Molecules: From Bench Tool to the Refined Drug
The depth and versatility of siRNA technologies enable their use in disease targets that are undruggable by small molecules or that seek to achieve a refined turn-off of the genes for any therapeutic area. Major extracellular barriers are enzymatic degradation of siRNAs by serum endonucleases and RN...
Autores principales: | de Brito e Cunha, Danielle, Frederico, Ana Beatriz Teixeira, Azamor, Tamiris, Melgaço, Juliana Gil, da Costa Neves, Patricia Cristina, Bom, Ana Paula Dinis Ano, Tilli, Tatiana Martins, Missailidis, Sotiris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146980/ https://www.ncbi.nlm.nih.gov/pubmed/35631401 http://dx.doi.org/10.3390/ph15050575 |
Ejemplares similares
-
Protective immunity after COVID-19 has been questioned: What can we do without SARS-CoV-2-IgG detection?
por: Melgaço, Juliana Gil, et al.
Publicado: (2020) -
Aptamers as Delivery Agents of siRNA and Chimeric Formulations for the Treatment of Cancer
por: Dinis Ano Bom, Ana Paula, et al.
Publicado: (2019) -
Impairment of CD4+ T and Memory B Cell Responses but Normal Memory CD8+T-Cell Activation on Crohn’s Disease after COVID-19 Vaccination: A Twin Case
por: Melgaço, Fabiana Gil, et al.
Publicado: (2021) -
Cellular and Molecular Immunology Approaches for the Development of Immunotherapies against the New Coronavirus (SARS-CoV-2): Challenges to Near-Future Breakthroughs
por: Melgaço, Juliana Gil, et al.
Publicado: (2020) -
Activation of an Effective Immune Response after Yellow Fever Vaccination Is Associated with the Genetic Background and Early Response of IFN-γ and CLEC5A
por: Azamor, Tamiris, et al.
Publicado: (2021)