New Treatment Strategies for IgA Nephropathy: Targeting Plasma Cells as the Main Source of Pathogenic Antibodies

Immunoglobulin A nephropathy (IgAN) is a rare autoimmune disorder and the leading cause of biopsy-reported glomerulonephritis (GN) worldwide. Disease progression is driven by the formation and deposition of immune complexes composed of galactose-deficient IgA1 (Gd-IgA1) and Gd-IgA1 autoantibodies (a...

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Detalles Bibliográficos
Autores principales: Maixnerova, Dita, El Mehdi, Delphine, Rizk, Dana V., Zhang, Hong, Tesar, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147021/
https://www.ncbi.nlm.nih.gov/pubmed/35628935
http://dx.doi.org/10.3390/jcm11102810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147021/
https://www.ncbi.nlm.nih.gov/pubmed/35628935
http://dx.doi.org/10.3390/jcm11102810

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