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New Treatment Strategies for IgA Nephropathy: Targeting Plasma Cells as the Main Source of Pathogenic Antibodies
Immunoglobulin A nephropathy (IgAN) is a rare autoimmune disorder and the leading cause of biopsy-reported glomerulonephritis (GN) worldwide. Disease progression is driven by the formation and deposition of immune complexes composed of galactose-deficient IgA1 (Gd-IgA1) and Gd-IgA1 autoantibodies (a...
Autores principales: | Maixnerova, Dita, El Mehdi, Delphine, Rizk, Dana V., Zhang, Hong, Tesar, Vladimir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147021/ https://www.ncbi.nlm.nih.gov/pubmed/35628935 http://dx.doi.org/10.3390/jcm11102810 |
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