Effect of Penetration Enhancers and Safety on the Transdermal Delivery of Apremilast in Skin

The poor water solubility of apremilast (APR) is the main impediment to the penetration of the drug through the skin barrier. The objective of this study was to evaluate the permeability of APR in different solutions enriched with penetration promoters in ex vivo samples of human skin, and additiona...

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Detalles Bibliográficos
Autores principales: Sarango-Granda, Paulo, Espinoza, Lupe Carolina, Díaz-Garrido, Natalia, Alvarado, Helen, Rodríguez-Lagunas, María J., Baldomá, Laura, Calpena, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147106/
https://www.ncbi.nlm.nih.gov/pubmed/35631597
http://dx.doi.org/10.3390/pharmaceutics14051011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147106/
https://www.ncbi.nlm.nih.gov/pubmed/35631597
http://dx.doi.org/10.3390/pharmaceutics14051011

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