Attenuation of Olanzapine-Induced Endoplasmic Reticulum Stress Improves Insulin Secretion in Pancreatic Beta Cells

Second-generation antipsychotics (SGAs), in particular, olanzapine and clozapine, have been associated with the development of type 2 diabetes mellitus (T2D) and metabolic syndrome in individuals with schizophrenia. In this context, beta cell dysfunction is a plausible mechanism by which SGAs cause...

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Detalles Bibliográficos
Autores principales: Grajales, Diana, Vázquez, Patricia, Alén, Rosa, Hitos, Ana B., Valverde, Ángela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147261/
https://www.ncbi.nlm.nih.gov/pubmed/35629947
http://dx.doi.org/10.3390/metabo12050443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147261/
https://www.ncbi.nlm.nih.gov/pubmed/35629947
http://dx.doi.org/10.3390/metabo12050443

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