Cargando…

Attenuation of Olanzapine-Induced Endoplasmic Reticulum Stress Improves Insulin Secretion in Pancreatic Beta Cells

Second-generation antipsychotics (SGAs), in particular, olanzapine and clozapine, have been associated with the development of type 2 diabetes mellitus (T2D) and metabolic syndrome in individuals with schizophrenia. In this context, beta cell dysfunction is a plausible mechanism by which SGAs cause...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grajales, Diana, Vázquez, Patricia, Alén, Rosa, Hitos, Ana B., Valverde, Ángela M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147261/ https://www.ncbi.nlm.nih.gov/pubmed/35629947 http://dx.doi.org/10.3390/metabo12050443

Ejemplares similares

PKR inhibitors suppress endoplasmic reticulum stress and subdue glucolipotoxicity-mediated impairment of insulin secretion in pancreatic beta cells
por: YALÇIN, Abdullah, et al.
Publicado: (2020)

Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model
por: Lay, Angelina J., et al.
Publicado: (2022)

Insulin Therapy for Pre-Hyperglycemic Beta-Cell Endoplasmic Reticulum Crowding
por: Absood, Afaf, et al.
Publicado: (2013)

Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells
por: Moon, Seoil, et al.
Publicado: (2022)

Palmitate is not an effective fuel for pancreatic islets and amplifies insulin secretion independent of calcium release from endoplasmic reticulum
por: Kuok, Iok Teng, et al.
Publicado: (2019)

Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes
por: Ninagawa, Satoshi, et al.
Publicado: (2020)

The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice
por: Grajales, Diana, et al.
Publicado: (2021)

Enhanced Wild-Type MET Receptor Levels in Mouse Hepatocytes Attenuates Insulin-Mediated Signaling
por: Rada, Patricia, et al.
Publicado: (2022)

Simultaneous Measurement of Changes in Mitochondrial and Endoplasmic Reticulum Free Calcium in Pancreatic Beta Cells
por: Jeyarajan, Sivakumar, et al.
Publicado: (2023)

Catestatin improves insulin sensitivity by attenuating endoplasmic reticulum stress: In vivo and in silico validation
por: Dasgupta, Abhijit, et al.
Publicado: (2020)

Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain
por: He, Meng, et al.
Publicado: (2021)

Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells
por: Hong, Seok-Woo, et al.
Publicado: (2018)

Endoplasmic Reticulum (ER) Stress in Part Mediates Effects of Angiotensin II in Pancreatic Beta Cells
por: Ramalingam, Latha, et al.
Publicado: (2020)

Role of endoplasmic reticulum domains in determining secretion routes
por: Seedorf, Matthias
Publicado: (2010)

Polysiphonia japonica Extract Attenuates Palmitate-Induced Toxicity and Enhances Insulin Secretion in Pancreatic Beta-Cells
por: Cha, Seon-Heui, et al.
Publicado: (2018)

Trafficking-defective mutant PROKR2 cycles between endoplasmic reticulum and Golgi to attenuate endoplasmic reticulum stress
por: Song, Yong Bhum, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress and Insulin Biosynthesis: A Review
por: Kim, Mi-Kyung, et al.
Publicado: (2012)

Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells
por: Stone, Stephen, et al.
Publicado: (2019)

Maternal stress induced endoplasmic reticulum stress and impaired pancreatic islets’ insulin secretion via glucocorticoid receptor upregulation in adult male rat offspring
por: Salimi, Mina, et al.
Publicado: (2022)

Endoplasmic reticulum stress inhibition ameliorated WFS1 expression alterations and reduced pancreatic islets’ insulin secretion induced by high-fat diet in rats
por: Binayi, Fateme, et al.
Publicado: (2023)

Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion
por: Debattisti, Valentina, et al.
Publicado: (2014)

Endoplasmic Reticulum Redox State Is Not Perturbed by Pharmacological or Pathological Endoplasmic Reticulum Stress in Live Pancreatic β-Cells
por: Schuiki, Irmgard, et al.
Publicado: (2012)

AGR2, an Endoplasmic Reticulum Protein, Is Secreted into the Gastrointestinal Mucus
por: Bergström, Joakim H., et al.
Publicado: (2014)

FENESTRAE IN THE ROUGH ENDOPLASMIC RETICULUM OF THE EXOCRINE PANCREATIC CELLS
por: Orci, Lelio, et al.
Publicado: (1972)

Fluvoxamine Attenuated Endoplasmic Reticulum Stress-Induced Leptin Resistance
por: Hosoi, Toru, et al.
Publicado: (2012)

Paclitaxel inhibits selenoprotein S expression and attenuates endoplasmic reticulum stress
por: QIN, HONG-SHUANG, et al.
Publicado: (2016)

THE ENDOPLASMIC RETICULUM
por: Palade, George E.
Publicado: (1956)

Intra-islet insulin synthesis defects are associated with endoplasmic reticulum stress and loss of beta cell identity in human diabetes
por: Brusco, Noemi, et al.
Publicado: (2022)

Fluoride Induces Endoplasmic Reticulum Stress and Inhibits Protein Synthesis and Secretion
por: Sharma, Ramaswamy, et al.
Publicado: (2008)

Combined Effects of Multiple Endoplasmic Reticulum Stresses on Cytokine Secretion in Macrophage
por: Kim, Hye Min, et al.
Publicado: (2012)

Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum
por: de Ruijter, Jorg C., et al.
Publicado: (2016)

Emphysematous pancreatitis predisposed by Olanzapine
por: Samanta, Sukhen, et al.
Publicado: (2014)

Irisin attenuates intestinal injury, oxidative and endoplasmic reticulum stress in mice with L-arginine-induced acute pancreatitis
por: Ren, Yi-Fan, et al.
Publicado: (2019)

Targeting Endoplasmic Reticulum Stress as an Effective Treatment for Alcoholic Pancreatitis
por: Li, Hui, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL
por: Plaisance, Valérie, et al.
Publicado: (2016)

MicroRNA-24 promotes pancreatic beta cells toward dedifferentiation to avoid endoplasmic reticulum stress-induced apoptosis
por: Zhu, Yunxia, et al.
Publicado: (2019)

Neuritin Attenuates Neuronal Apoptosis Mediated by Endoplasmic Reticulum Stress In Vitro
por: Sun, Xiaokun, et al.
Publicado: (2018)

Andrographolide contributes to the attenuation of cardiac hypertrophy by suppressing endoplasmic reticulum stress
por: Tian, Qingxin, et al.
Publicado: (2022)

SAT074 Induction Of Insulin Hypersecretion Uncovers Distinctions Between Adaptive And Maladaptive Endoplasmic Reticulum Stress Response In Beta Cells
por: Roy, Gitanjali, et al.
Publicado: (2023)

Deficient Endoplasmic Reticulum Acetyl-CoA Import in Pancreatic Acinar Cells Leads to Chronic Pancreatitis
por: Cooley, Michelle M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6kvshfdoeer9fpe58a4sa2qd72