Polymorphic Molecular Signatures in Variable Regions of the Plasmodium falciparum var2csa DBL3x Domain Are Associated with Virulence in Placental Malaria

The Plasmodium falciparum protein VAR2CSA allows infected erythrocytes to accumulate within the placenta, inducing pathology and poor birth outcomes. Multiple exposures to placental malaria (PM) induce partial immunity against VAR2CSA, making it a promising vaccine candidate. However, the extent to...

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Detalles Bibliográficos
Autores principales: Talundzic, Eldin, Scott, Stephen, Owino, Simon O., Campo, David S., Lucchi, Naomi W., Udhayakumar, Venkatachalam, Moore, Julie M., Peterson, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147263/
https://www.ncbi.nlm.nih.gov/pubmed/35631041
http://dx.doi.org/10.3390/pathogens11050520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147263/
https://www.ncbi.nlm.nih.gov/pubmed/35631041
http://dx.doi.org/10.3390/pathogens11050520

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