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Hydroxychloroquine Does Not Function as a Direct Zinc Ionophore

Drug-mediated correction of abnormal biological zinc homeostasis could provide new routes to treating neurodegeneration, cancer, and viral infections. Designing therapeutics to facilitate zinc transport intracellularly is hampered by inadequate concentrations of endogenous zinc, which is often prote...

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Detalles Bibliográficos
Autores principales: Kavanagh, Oisín N., Bhattacharya, Shayon, Marchetti, Luke, Elmes, Robert, O’Sullivan, Finbarr, Farragher, John P., Robinson, Shane, Thompson, Damien, Walker, Gavin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147311/
https://www.ncbi.nlm.nih.gov/pubmed/35631485
http://dx.doi.org/10.3390/pharmaceutics14050899