Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron

In this report, we mechanistically reveal how the Variant of Concern (VOC) SARS-CoV-2 Omicron (B.1.1.529) escapes neutralizing antibody responses, by physio-chemical characterization of this variant in comparison to the wild-type Wuhan and the Delta variant (B.1.617.2). Convalescent sera, as well as...

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Detalles Bibliográficos
Autores principales: Vogt, Anne-Cathrine S., Augusto, Gilles, Martina, Byron, Chang, Xinyue, Nasrallah, Gheyath, Speiser, Daniel E., Vogel, Monique, Bachmann, Martin F., Mohsen, Mona O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147318/
https://www.ncbi.nlm.nih.gov/pubmed/35632499
http://dx.doi.org/10.3390/vaccines10050743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147318/
https://www.ncbi.nlm.nih.gov/pubmed/35632499
http://dx.doi.org/10.3390/vaccines10050743

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