NF-κB-Induced R-Loops and Genomic Instability in HTLV-1-Infected and Adult T-Cell Leukemia Cells

Human T-cell leukemia virus type 1 (HTLV-1) is a human delta retrovirus that causes adult T-cell leukemia/lymphoma (ATL) in 3–5% of the infected population after decades of clinical latency. HTLV-1 Tax is a potent activator of IKK/NF-κB and a clastogen. While NF-κB activities are associated with cel...

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Detalles Bibliográficos
Autores principales: Giam, Chou-Zen, Pasupala, Nagesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147355/
https://www.ncbi.nlm.nih.gov/pubmed/35632619
http://dx.doi.org/10.3390/v14050877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147355/
https://www.ncbi.nlm.nih.gov/pubmed/35632619
http://dx.doi.org/10.3390/v14050877

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