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Tofacitinib May Inhibit Myofibroblast Differentiation from Rheumatoid-Fibroblast-like Synoviocytes Induced by TGF-β and IL-6

During rheumatoid arthritis (RA), the pathogenic role of resident cells within the synovial membrane is suggested, especially for a population frequently referred to as fibroblast-like synoviocytes (FLSs). In this study, we assess the markers of myofibroblast differentiation of RA-FLSs by ex vivo ob...

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Detalles Bibliográficos
Autores principales: Ruscitti, Piero, Liakouli, Vasiliki, Panzera, Noemi, Angelucci, Adriano, Berardicurti, Onorina, Di Nino, Elena, Navarini, Luca, Vomero, Marta, Ursini, Francesco, Mauro, Daniele, Dolo, Vincenza, Ciccia, Francesco, Giacomelli, Roberto, Cipriani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147406/
https://www.ncbi.nlm.nih.gov/pubmed/35631449
http://dx.doi.org/10.3390/ph15050622