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Huntingtin Co-Isolates with Small Extracellular Vesicles from Blood Plasma of TgHD and KI-HD Pig Models of Huntington’s Disease and Human Blood Plasma

(1) Background: Huntington’s disease (HD) is rare incurable hereditary neurodegenerative disorder caused by CAG repeat expansion in the gene coding for the protein huntingtin (HTT). Mutated huntingtin (mHTT) undergoes fragmentation and accumulation, affecting cellular functions and leading to neuron...

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Detalles Bibliográficos
Autores principales: Ananbeh, Hanadi, Novak, Jaromir, Juhas, Stefan, Juhasova, Jana, Klempir, Jiri, Doleckova, Kristyna, Rysankova, Irena, Turnovcova, Karolina, Hanus, Jaroslav, Hansikova, Hana, Vodicka, Petr, Kupcova Skalnikova, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147436/
https://www.ncbi.nlm.nih.gov/pubmed/35628406
http://dx.doi.org/10.3390/ijms23105598