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Huntingtin Co-Isolates with Small Extracellular Vesicles from Blood Plasma of TgHD and KI-HD Pig Models of Huntington’s Disease and Human Blood Plasma
(1) Background: Huntington’s disease (HD) is rare incurable hereditary neurodegenerative disorder caused by CAG repeat expansion in the gene coding for the protein huntingtin (HTT). Mutated huntingtin (mHTT) undergoes fragmentation and accumulation, affecting cellular functions and leading to neuron...
Autores principales: | Ananbeh, Hanadi, Novak, Jaromir, Juhas, Stefan, Juhasova, Jana, Klempir, Jiri, Doleckova, Kristyna, Rysankova, Irena, Turnovcova, Karolina, Hanus, Jaroslav, Hansikova, Hana, Vodicka, Petr, Kupcova Skalnikova, Helena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147436/ https://www.ncbi.nlm.nih.gov/pubmed/35628406 http://dx.doi.org/10.3390/ijms23105598 |
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