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The Study of Cyclosporin A Nanocrystals Uptake and Transport across an Intestinal Epithelial Cell Model

Cyclosporin A nanocrystals (CsA-NCs) interaction with Caco-2 cells were investigated in this study, including cellular uptake and transport across Caco-2 cell monolayers. CsA-NCs of 165 nm, 240 nm and 450 nm were formulated. The dissolution of CsA-NCs was investigated by paddle method. The effect of...

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Detalles Bibliográficos
Autores principales: Sun, Wenjun, Tian, Yang, Wang, Zengming, Zhang, Hui, Zheng, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147483/
https://www.ncbi.nlm.nih.gov/pubmed/35631858
http://dx.doi.org/10.3390/polym14101975