Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments

Purpose: RANKL expression in the tumor microenvironment has been identified as a biomarker of immune suppression, negating the effect of some cancer immunotherapies. Previously we had developed a radiotracer based on the FDA-approved RANKL-specific antibody denosumab, [(89)Zr]Zr-DFO-denosumab, enabl...

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Detalles Bibliográficos
Autores principales: Dewulf, Jonatan, Hrynchak, Ivanna, Geudens, Sarah, Pintelon, Isabel, Vangestel, Christel, Sereno, José, van Dam, Peter A., Abrunhosa, Antero J., Elvas, Filipe, Van den Wyngaert, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147590/
https://www.ncbi.nlm.nih.gov/pubmed/35631525
http://dx.doi.org/10.3390/pharmaceutics14050939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147590/
https://www.ncbi.nlm.nih.gov/pubmed/35631525
http://dx.doi.org/10.3390/pharmaceutics14050939

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