The Antitumoral/Antimetastatic Action of the Flavonoid Brachydin A in Metastatic Prostate Tumor Spheroids In Vitro Is Mediated by (Parthanatos) PARP-Related Cell Death

Metastatic prostate cancer (mPCa) is resistant to several chemotherapeutic agents. Brachydin A (BrA), a glycosylated flavonoid extracted from Fridericia platyphylla, displays a remarkable antitumoral effect against in vitro mPCa cells cultured as bidimensional (2D) monolayers. Considering that three...

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Detalles Bibliográficos
Autores principales: Ribeiro, Diego Luis, Tuttis, Katiuska, de Oliveira, Larissa Cristina Bastos, Serpeloni, Juliana Mara, Gomes, Izabela Natalia Faria, Lengert, André van Helvoort, da Rocha, Cláudia Quintino, Reis, Rui Manuel, Cólus, Ilce Mara de Syllos, Antunes, Lusânia Maria Greggi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147598/
https://www.ncbi.nlm.nih.gov/pubmed/35631550
http://dx.doi.org/10.3390/pharmaceutics14050963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147598/
https://www.ncbi.nlm.nih.gov/pubmed/35631550
http://dx.doi.org/10.3390/pharmaceutics14050963

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