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Development of a 96-Well Electrophilic Allergen Screening Assay for Skin Sensitization Using a Measurement Science Approach

The Electrophilic Allergen Screening Assay (EASA) has emerged as a promising in chemico method to detect the first key event in the adverse outcome pathway (AOP) for skin sensitization. This assay functions by assessing the depletion of one of two probe molecules (4-nitrobenzenethiol (NBT) and pyrid...

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Detalles Bibliográficos
Autores principales: Petersen, Elijah J., Uhl, Richard, Toman, Blaza, Elliott, John T., Strickland, Judy, Truax, James, Gordon, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147637/
https://www.ncbi.nlm.nih.gov/pubmed/35622670
http://dx.doi.org/10.3390/toxics10050257