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Development of a 96-Well Electrophilic Allergen Screening Assay for Skin Sensitization Using a Measurement Science Approach
The Electrophilic Allergen Screening Assay (EASA) has emerged as a promising in chemico method to detect the first key event in the adverse outcome pathway (AOP) for skin sensitization. This assay functions by assessing the depletion of one of two probe molecules (4-nitrobenzenethiol (NBT) and pyrid...
Autores principales: | Petersen, Elijah J., Uhl, Richard, Toman, Blaza, Elliott, John T., Strickland, Judy, Truax, James, Gordon, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147637/ https://www.ncbi.nlm.nih.gov/pubmed/35622670 http://dx.doi.org/10.3390/toxics10050257 |
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