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Oral Immunization of Chickens with Probiotic Lactobacillus crispatus Constitutively Expressing the α-β2-ε-β1 Toxoids to Induce Protective Immunity

Clostridium perfringens (C. perfringens) is a bacterium that commonly causes zoonotic disease. The pathogenicity of C. perfringens is a result of the combined action of α, β, and ε exotoxins. In this study, Lactobacillus crispatus (pPG-T7g10/L. crispatus) expressing the main toxoids of C. perfringen...

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Detalles Bibliográficos
Autores principales: Khan, Mohammad Zeb, Li, Fengsai, Huang, Xuewei, Nouman, Muhammad, Bibi, Roshna, Fan, Xiaolong, Zhou, Han, Shan, Zhifu, Wang, Li, Jiang, Yanping, Cui, Wen, Qiao, Xinyuan, Li, Yijing, Wang, Xiaona, Tang, Lijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147743/
https://www.ncbi.nlm.nih.gov/pubmed/35632454
http://dx.doi.org/10.3390/vaccines10050698