The Novel Function of Unsymmetrical Chiral CCN Pincer Nickel Complexes as Chemotherapeutic Agents Targeting Prostate Cancer Cells

We report that the pincer nickel complexes display prostate cancer antitumor properties through inhibition of cell proliferation. Notably, they display better antitumor properties than cisplatin. Mechanistic studies reveal that these pincer nickel complexes trigger cell apoptosis, most likely due to...

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Detalles Bibliográficos
Autores principales: Qu, Jing-Jing, Shi, Lin-Lin, Wang, Yan-Bing, Yan, Jing, Shao, Tian, Hao, Xin-Qi, Wang, Jia-Xiang, Zhang, Hong-Yu, Gong, Jun-Fang, Song, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147786/
https://www.ncbi.nlm.nih.gov/pubmed/35630591
http://dx.doi.org/10.3390/molecules27103106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147786/
https://www.ncbi.nlm.nih.gov/pubmed/35630591
http://dx.doi.org/10.3390/molecules27103106

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