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The Novel Function of Unsymmetrical Chiral CCN Pincer Nickel Complexes as Chemotherapeutic Agents Targeting Prostate Cancer Cells
We report that the pincer nickel complexes display prostate cancer antitumor properties through inhibition of cell proliferation. Notably, they display better antitumor properties than cisplatin. Mechanistic studies reveal that these pincer nickel complexes trigger cell apoptosis, most likely due to...
Autores principales: | Qu, Jing-Jing, Shi, Lin-Lin, Wang, Yan-Bing, Yan, Jing, Shao, Tian, Hao, Xin-Qi, Wang, Jia-Xiang, Zhang, Hong-Yu, Gong, Jun-Fang, Song, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147786/ https://www.ncbi.nlm.nih.gov/pubmed/35630591 http://dx.doi.org/10.3390/molecules27103106 |
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