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BUB3, beyond the Simple Role of Partner

The BUB3 protein plays a key role in the activation of the spindle assembly checkpoint (SAC), a ubiquitous surveillance mechanism that ensures the fidelity of chromosome segregation in mitosis and, consequently, prevents chromosome mis-segregation and aneuploidy. Besides its role in SAC signaling, B...

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Detalles Bibliográficos
Autores principales: Silva, Patrícia M. A., Bousbaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147866/
https://www.ncbi.nlm.nih.gov/pubmed/35631670
http://dx.doi.org/10.3390/pharmaceutics14051084