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Translational Medicine in Uremic Vascular Calcification: Scavenging ROS Attenuates p-Cresyl Sulfate-Activated Caspase-1, NLRP3 Inflammasome and Eicosanoid Inflammation in Human Arterial Smooth Muscle Cells

We formerly proved that uremic vascular calcification (UVC) correlates tightly with oxidative elastic lamina (EL) injury and two cell fates (apoptosis and osteocytic conversion) in smooth muscle cells (SMC) of chronic kidney disease (CKD) patients and eliminating p-cresyl sulfate (PCS)-activated int...

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Detalles Bibliográficos
Autores principales: Chang, Jia-Feng, Kuo, Hsiao-Ling, Liu, Shih-Hao, Hsieh, Chih-Yu, Hsu, Chih-Ping, Hung, Kuo-Chin, Wang, Ting-Ming, Wu, Chang-Chin, Lu, Kuo-Cheng, Lin, Wei-Ning, Hung, Chi-Feng, Ko, Wen-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147867/
https://www.ncbi.nlm.nih.gov/pubmed/35629435
http://dx.doi.org/10.3390/life12050769