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The Increase of miR-195-5p Reduces Intestinal Permeability in Ulcerative Colitis, Modulating Tight Junctions’ Expression

Defects in the intestinal epithelial barrier functions characterize inflammatory conditions such as Inflammatory Bowel Disease (IBD). Overexpression of pro-inflammatory cytokines such as TNF-α, IL-1B, IL-6 and INF-γ trigger epithelial damage. These cytokines are due to upregulation of claudin-2 (CLD...

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Detalles Bibliográficos
Autores principales: Scalavino, Viviana, Piccinno, Emanuele, Bianco, Giusy, Schena, Nicolò, Armentano, Raffaele, Giannelli, Gianluigi, Serino, Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147977/
https://www.ncbi.nlm.nih.gov/pubmed/35628650
http://dx.doi.org/10.3390/ijms23105840