Development and Characterization of a Factor V-Deficient CRISPR Cell Model for the Correction of Mutations

Factor V deficiency, an ultra-rare congenital coagulopathy, is characterized by bleeding episodes that may be more or less intense as a function of the levels of coagulation factor activity present in plasma. Fresh-frozen plasma, often used to treat patients with factor V deficiency, is a scarcely e...

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Detalles Bibliográficos
Autores principales: Serrano, Luis Javier, Garcia-Arranz, Mariano, De Pablo-Moreno, Juan A., Segovia, José Carlos, Olivera-Salazar, Rocío, Garcia-Olmo, Damián, Liras, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148015/
https://www.ncbi.nlm.nih.gov/pubmed/35628611
http://dx.doi.org/10.3390/ijms23105802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148015/
https://www.ncbi.nlm.nih.gov/pubmed/35628611
http://dx.doi.org/10.3390/ijms23105802

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