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Bioassay-Guided Isolation of 2-[p-(2-Carboxyhydrazino)phenoxy]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol from Oroxylum indicum and the Investigation of Its Molecular Mechanism Action of Apoptosis Induction

The leaf crude extract of Oroxylum indicum (L.) Kurz induces genomic DNA fragmentation, comet formation, and the inhibition of cell proliferation in the prostate cancer cell line PC3, as assessed by agarose gel electrophoresis, comet assay and MTT assay, respectively. The bioactive compound was puri...

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Detalles Bibliográficos
Autores principales: Singh, Asem Robinson, Singh, Salam Asbin, Singh, Thangjam Davis, Singh, Naorem Tarundas, Machathoibi, Takhellambam Chanu, Singh, Okram Mukherjee, Singh, Lisam Shanjukumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148098/
https://www.ncbi.nlm.nih.gov/pubmed/35631385
http://dx.doi.org/10.3390/ph15050559