Novel Luteolin-Loaded Chitosan Decorated Nanoparticles for Brain-Targeting Delivery in a Sporadic Alzheimer’s Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways

Preparation and evaluation of a non-invasive intranasal luteolin delivery for the management of cognitive dysfunction in Alzheimer’s disease (AD) using novel chitosan decorated nanoparticles. Development of luteolin-loaded chitosomes was followed by full in vitro characterization. In vivo efficacy w...

Descripción completa

Detalles Bibliográficos
Autores principales: Abbas, Haidy, Sayed, Nesrine S El, Youssef, Nancy Abdel Hamid Abou, M. E. Gaafar, Passent, Mousa, Mohamed R., Fayez, Ahmed M., Elsheikh, Manal A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148113/
https://www.ncbi.nlm.nih.gov/pubmed/35631589
http://dx.doi.org/10.3390/pharmaceutics14051003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148113/
https://www.ncbi.nlm.nih.gov/pubmed/35631589
http://dx.doi.org/10.3390/pharmaceutics14051003

Ejemplares similares