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Novel Luteolin-Loaded Chitosan Decorated Nanoparticles for Brain-Targeting Delivery in a Sporadic Alzheimer’s Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways
Preparation and evaluation of a non-invasive intranasal luteolin delivery for the management of cognitive dysfunction in Alzheimer’s disease (AD) using novel chitosan decorated nanoparticles. Development of luteolin-loaded chitosomes was followed by full in vitro characterization. In vivo efficacy w...
Autores principales: | Abbas, Haidy, Sayed, Nesrine S El, Youssef, Nancy Abdel Hamid Abou, M. E. Gaafar, Passent, Mousa, Mohamed R., Fayez, Ahmed M., Elsheikh, Manal A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148113/ https://www.ncbi.nlm.nih.gov/pubmed/35631589 http://dx.doi.org/10.3390/pharmaceutics14051003 |
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