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GLP-1R Agonist Exendin-4 Protects Against Hemorrhagic Transformation Induced by rtPA After Ischemic Stroke via the Wnt/β-Catenin Signaling Pathway

Tissue plasminogen activator (tPA) is recommended by the FDA to dissolve intravascular clots after acute ischemic stroke (AIS). However, it may contribute to hemorrhagic transformation (HT). The Wnt/β-catenin signaling pathway plays an important role in regulating the blood–brain barrier (BBB) forma...

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Detalles Bibliográficos
Autores principales: Liu, Chengli, Sun, Shanshan, Xie, Jie, Li, Hui, Li, Tianyu, Wu, Qiqi, Zhang, Yongsheng, Bai, Xiangjun, Wang, Jian, Wang, Xin, Li, Zhanfei, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148281/
https://www.ncbi.nlm.nih.gov/pubmed/35359227
http://dx.doi.org/10.1007/s12035-022-02811-9