MyD88 Deficiency, but Not Gut Microbiota Depletion, Is Sufficient to Modulate the Blood–Brain Barrier Function in the Mediobasal Hypothalamus

Circumventricular organs (CVOs), including the mediobasal hypothalamus (MBH), have an incomplete blood–brain barrier (BBB). In this study, we determined if the BBB function in the MBH is modulated by the gut microbiota or by the Toll-like receptor (TLR) adapter proteins TRIF or MyD88 signaling. By i...

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Detalles Bibliográficos
Autores principales: Heiss, Christina N., Gravert, Ellinor, Hultén, Matilda, Olofsson, Louise E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148286/
https://www.ncbi.nlm.nih.gov/pubmed/35381888
http://dx.doi.org/10.1007/s12035-022-02802-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148286/
https://www.ncbi.nlm.nih.gov/pubmed/35381888
http://dx.doi.org/10.1007/s12035-022-02802-w

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