HDAC3 Inhibition Stimulates Myelination in a CMT1A Mouse Model

Charcot–Marie–Tooth disease (CMT) is the most common inherited peripheral neuropathy, with currently no effective treatment or cure. CMT1A is caused by a duplication of the PMP22 gene, which leads to Schwann cell differentiation defects and dysmyelination of the peripheral nerves. The epigenetic reg...

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Detalles Bibliográficos
Autores principales: Prior, Robert, Verschoren, Stijn, Vints, Katlijn, Jaspers, Tom, Rossaert, Elisabeth, Klingl, Yvonne E., Silva, Alessio, Hersmus, Nicole, Van Damme, Philip, Van Den Bosch, Ludo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148289/
https://www.ncbi.nlm.nih.gov/pubmed/35320455
http://dx.doi.org/10.1007/s12035-022-02782-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148289/
https://www.ncbi.nlm.nih.gov/pubmed/35320455
http://dx.doi.org/10.1007/s12035-022-02782-x

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