Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study

Cerebral glucose hypometabolism is a typical hallmark of Alzheimer’s disease (AD), usually associated with ongoing neurodegeneration and neuronal dysfunction. However, underlying pathological processes are not fully understood and reproducibility in animal models is not well established. The aim of...

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Detalles Bibliográficos
Autores principales: Endepols, Heike, Anglada-Huguet, Marta, Mandelkow, Eckhard, Schmidt, Yannick, Krapf, Philipp, Zlatopolskiy, Boris D., Neumaier, Bernd, Mandelkow, Eva-Maria, Drzezga, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148291/
https://www.ncbi.nlm.nih.gov/pubmed/35312967
http://dx.doi.org/10.1007/s12035-022-02793-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148291/
https://www.ncbi.nlm.nih.gov/pubmed/35312967
http://dx.doi.org/10.1007/s12035-022-02793-8

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