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Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study
Cerebral glucose hypometabolism is a typical hallmark of Alzheimer’s disease (AD), usually associated with ongoing neurodegeneration and neuronal dysfunction. However, underlying pathological processes are not fully understood and reproducibility in animal models is not well established. The aim of...
Autores principales: | Endepols, Heike, Anglada-Huguet, Marta, Mandelkow, Eckhard, Schmidt, Yannick, Krapf, Philipp, Zlatopolskiy, Boris D., Neumaier, Bernd, Mandelkow, Eva-Maria, Drzezga, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148291/ https://www.ncbi.nlm.nih.gov/pubmed/35312967 http://dx.doi.org/10.1007/s12035-022-02793-8 |
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