Binding of the HSF-1 DNA-binding domain to multimeric C. elegans consensus HSEs is guided by cooperative interactions

The protein HSF-1 is the controlling transcription factor of the heat-shock response (HSR). Its binding to the heat-shock elements (HSEs) induces the strong upregulation of conserved heat-shock proteins, including Hsp70s, Hsp40s and small HSPs. Next to these commonly known HSPs, more than 4000 other...

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Detalles Bibliográficos
Autores principales: Schmauder, Lukas, Sima, Siyuan, Hadj, Amira Ben, Cesar, Ricardo, Richter, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148306/
https://www.ncbi.nlm.nih.gov/pubmed/35643773
http://dx.doi.org/10.1038/s41598-022-12736-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148306/
https://www.ncbi.nlm.nih.gov/pubmed/35643773
http://dx.doi.org/10.1038/s41598-022-12736-x

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