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Newly identified breast luminal progenitor and gestational stem cell populations likely give rise to HER2-overexpressing and basal-like breast cancers

Breast Cancer (BrC) is a common malignancy with genetically diverse subtypes. There is evidence that specific BrC subtypes originate from particular normal mammary cell populations. However, the cell populations that give rise to most BrC subtypes are unidentified. Several human breast scRNAseq data...

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Detalles Bibliográficos
Autores principales: McMullen, James R. W., Soto, Ubaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148339/
https://www.ncbi.nlm.nih.gov/pubmed/35633393
http://dx.doi.org/10.1007/s12672-022-00500-6