Rare variant association study of veteran twin whole-genomes links severe depression with a nonsynonymous change in the neuronal gene BHLHE22

OBJECTIVES: Major Depressive Disorder (MDD) is a complex neuropsychiatric disease with known genetic associations, but without known links to rare variation in the human genome. Here we aim to identify rare genetic variants associated with MDD using deep whole-genome sequencing data in an independen...

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Detalles Bibliográficos
Autores principales: Hupalo, Daniel, Forsberg, Christopher W., Goldberg, Jack, Kremen, William S., Lyons, Michael J., Soltis, Anthony R., Viollet, Coralie, Ursano, Robert J., Stein, Murray B., Franz, Carol E., Sun, Yan V., Vaccarino, Viola, Smith, Nicholas L., Dalgard, Clifton L., Wilkerson, Matthew D., Pollard, Harvey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148382/
https://www.ncbi.nlm.nih.gov/pubmed/34664540
http://dx.doi.org/10.1080/15622975.2021.1980316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148382/
https://www.ncbi.nlm.nih.gov/pubmed/34664540
http://dx.doi.org/10.1080/15622975.2021.1980316

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