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Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers

OBJECTIVE(S): Recently, great attention has been paid to developing new drug delivery systems to manage the rate, time, and site of drug release. We aimed to design a novel drug delivery system to support targeted and gradual delivery of levothyroxine sodium. MATERIALS AND METHODS: The triblock copo...

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Detalles Bibliográficos
Autores principales: Movaffagh, Jebraeil, Hadizadeh, Farzin, Khodaverdi, Elham, Khalili, Bahnaz, Rezaeian Shiadeh, Seyedeh Nesa, Kamali, Hossein, Oroojalian, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148395/
https://www.ncbi.nlm.nih.gov/pubmed/35656181
http://dx.doi.org/10.22038/IJBMS.2022.62576.13842