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Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach

OBJECTIVE(S): Brain cancer treatments have mainly failed due to their inability to cross the blood-brain barrier. Several studies have confirmed the presence of glutathione (GSH) receptors on BBB’s surface, as a result, products like 2B3-101, which contain over 5% pre-inserted GSH PEGylated liposoma...

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Detalles Bibliográficos
Autores principales: Mehrabian, Amin, Vakili-Ghartavol, Roghayyeh, Mashreghi, Mohammad, Shokooh Saremi, Sara, Badiee, Ali, Arabi, Leila, Alavizadeh, Seyedeh Hoda, Moosavian, Seyedeh Alia, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148397/
https://www.ncbi.nlm.nih.gov/pubmed/35656188
http://dx.doi.org/10.22038/IJBMS.2022.60306.13369