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Are mitophagy enhancers therapeutic targets for Alzheimer’s disease?

Healthy mitochondria are essential for functional bioenergetics, calcium signaling, and balanced redox homeostasis. Dysfunctional mitochondria are a central aspect of aging and neurodegenerative diseases such as Alzheimer’s disease (AD). The formation and accumulation of amyloid beta (Aβ) and hyperp...

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Detalles Bibliográficos
Autores principales: Pradeepkiran, Jangampalli Adi, Hindle, Ashly, Kshirsagar, Sudhir, Reddy, P. Hemachandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148418/
https://www.ncbi.nlm.nih.gov/pubmed/35585708
http://dx.doi.org/10.1016/j.biopha.2022.112918