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Are mitophagy enhancers therapeutic targets for Alzheimer’s disease?
Healthy mitochondria are essential for functional bioenergetics, calcium signaling, and balanced redox homeostasis. Dysfunctional mitochondria are a central aspect of aging and neurodegenerative diseases such as Alzheimer’s disease (AD). The formation and accumulation of amyloid beta (Aβ) and hyperp...
Autores principales: | Pradeepkiran, Jangampalli Adi, Hindle, Ashly, Kshirsagar, Sudhir, Reddy, P. Hemachandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148418/ https://www.ncbi.nlm.nih.gov/pubmed/35585708 http://dx.doi.org/10.1016/j.biopha.2022.112918 |
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